Loss of HLTF function promotes intestinal carcinogenesis
نویسندگان
چکیده
منابع مشابه
Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis.
Despite the significance of oxidative damage for carcinogenesis, the molecular mechanisms that lead to increased susceptibility of tissues to oxidative stress are not well-understood. We now report a link between loss of protection against oxidative damage and loss-of-function of Nkx3.1, a homeobox gene that is known to be required for prostatic epithelial differentiation and suppression of pro...
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ژورنال
عنوان ژورنال: Molecular Cancer
سال: 2012
ISSN: 1476-4598
DOI: 10.1186/1476-4598-11-18